Faili:Serpin equilibrium.png

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Muhtasari

Maelezo
English: The native state of serpins is an equilibrium between a fully-stressed state (left) and a partially relaxed state (right). The five-stranded A-sheet (light blue) contains two functionally important regions for the serpin's mechanism, the breach and the shutter. The Reactive Centre Loop (RCL, blue) exists in a dynamic equilibrium between the fully exposed conformation (left) and a conformation where it is partially inserted into the breach of the A-sheet (right). (PDB: 1QLP, 1YXA​). [1] [2]
Tarehe
Chanzo Kazi yangu
Mwandishi Thomas Shafee

Hatimiliki

I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
sifa
This file is licensed under the Creative Commons Attribution 4.0 International license.
Uko huru:
  • kushiriki – kunakili na kusambaza kazi hiyo
  • kwa remix – kurekebisha kazi
Chini ya masharti yafuatayo:
  • sifa – Ni lazima utoe mkopo unaofaa, utoe kiungo cha leseni, na uonyeshe ikiwa mabadiliko yalifanywa. Unaweza kufanya hivyo kwa njia yoyote inayofaa, lakini si kwa njia yoyote inayopendekeza mtoa leseni akuidhinishe wewe au matumizi yako.
  1. ↑ Elliott PR, Lomas DA, Carrell RW, Abrahams JP. (1996). "Inhibitory conformation of the reactive loop of alpha 1-antitrypsin". Nature Structural & Molecular Biology 3 (8): 676–81. DOI:10.1038/nsb0896-676. PMID 8756325.
  2. ↑ (2005). "The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.". J Biol Chem 280 (52): 43168–78. DOI:10.1074/jbc.M505598200. PMID 16141197.

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Tarehe/SaaPicha ndogoVipimoMtumiajiMaelezo
sasa hivi23:23, 6 Oktoba 2016Picha ndogo ya toleo la 23:23, 6 Oktoba 20163,000 × 1,902 (1.41 MB)CmdrjamesonCompressed with pngout. Reduced by 772kB (34% decrease).
23:05, 19 Machi 2016Picha ndogo ya toleo la 23:05, 19 Machi 20163,000 × 1,902 (2.16 MB)Evolution and evolvabilityColour tweaks
12:05, 14 Desemba 2015Picha ndogo ya toleo la 12:05, 14 Desemba 20151,246 × 765 (476 KB)Evolution and evolvabilityCross-wiki upload from en.wikipedia.org

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